Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

8.Russia
"We're excited to have these talented artists showcase the powerful contribution music makes to filmmaking," the show's producers Michael De Luca and Jennifer Todd announced in a statement on Friday. "It's a privilege to welcome them to the 90th Oscars stage."
卡尔还表示:“就算没有厄尔尼诺现象,去年气温也有可能创纪录,但厄尔尼诺现象让高温更加极端。”
The UK’s Warwick Business School recorded the best progression at the top, moving up from 16th to ninth place, while the Shanghai Advanced Institute of Finance (Saif), based at JiaoTong University, enjoys the bestprogression overall, jumping from 28th to 14th place.
卡恩称,Summly的机器学习和自然语言处理能力背后的设想和技术“均很出色”。
Agents and investment institutions are now flooding the sector, causing additional changes to the platforms in the world's second-largest economy, the report said.
投资者也关注到了本田的这一困境。尽管在席卷全球的金融危机中,本田是全球少数几家能独善其身、避免严重亏损的汽车厂商之一,但在过去几年中,其普通股股价下跌了17.2%,而同期日经225指数却上涨了7.4%,丰田汽车的股价也上涨了19.5%。
~z+_86mGYj-!oA@9!E!0.wYCqmDvF4
标有*符号的奖项已于9月10日到11日举行的艾美奖创新艺术典礼上公布。
The cyclical theory depends on a dearth of new investment creating a supply crunch in two, three or five years. A lot of projects are being postponed but postponement is no more than a signal to project managers to find a way of cutting costs. Many are doing exactly that.
So, yeah, I think they should tank and they might even be able to get some good value for Ibaka in a trade even if it would be a really quick about-face. God they're weird.
5.匈牙利德布勒森
That comes in spite of official figures released on Tuesday showing China’s exports had contracted for a second straight month in October, suggesting domestic demand is the main driver of price gains for producers.
consciousness
麦高恩出生于多配偶制的邪教家庭,少年时离家出走。
The board is frequently covered in equations. Have you ever wondered what those equations mean? Well, we may never know what they mean, but they are all real, accurate equations. Very impressive, Big Bang. Very impressive indeed.
时间:2010-05-31 编辑:francie
据《21世纪经济报道》称,广东去年的GDP增速为7.5%。
4. Con Dao Isalsnd, Vietnam-Once the site of the infamous Con Dao prison, Vietnam's isolated archipelago of 16 islands known as the Con Dao Islands is starting to become known for its scenery and fresh seafood.
高通(Qualcomm)总部所在地的农民们肯定像它的雇员一样超爱这家无线电公司。每周,高通会在其总部圣地亚哥择址两处举办农夫市集。出售的商品从传统农产品到果酱、果冻无所不包。凡是订购了“社区支持农业”素食礼盒的高通雇员,在总部的一家咖啡馆即可轻松收货。
张景岫说:“学生本身并不适合创业。”他补充说道,职业院校的学生比大学生更渴望自主创业。
Gongloff piles on the bad news about 2014: GDP 'grew at a 1.8% annualized pace in the first quarter ... revising down its earlier estimate of 2.4% growth ... The first quarter's dismal growth was at least better than the 0.4% GDP growth of the fourth quarter of 2012. But it was still far from healthy, and economists don't see it getting much stronger any time soon.' And that's real bad news for the markets going into 2014.
排球拳击乒乓球举重沙滩排球铁人三项艺术体操蹦床篮球射击羽毛球艺术体操足球网球
我们坐在这里指点江山,告诉那些球队“你们没指望了,赶紧输球摆烂吧!”这是很容易的,但是我们并不是那些在为球队门票和广告殚精竭虑的家伙们。
Nevertheless, as New Yorkers grow accustomed to a sharing economy, buildings might ultimately have to embrace it.


卡利南和瑞兹各提一只装着所有奖项结果信封的手提箱——也就是说,每个奖项都有两只信封。
I, however, am not among them.
中国富人近年来对岛屿表现出越来越浓厚的兴趣。


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

智能床垫
Chinese people are intelligent and hardworking and they have an inexhaustible drive for pursuing a better life for themselves. The government needs to create the enabling environment for our people to fully use their talent and initiative.
据中国新闻报道,在2011此墓主人被认定为刘非(公元前169-127),汉朝诸侯国江都第一任国君。
In total, Chinese mainland has 54 institutions in the listing of top 300 universities in Asia.

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

The Iranian dissident filmmaker, posing as a (barely competent) Tehran cabdriver, stages a sly, pseudo-documentary inquiry into the paradoxes of cinema and the contradictions of everyday life under authoritarian rule.

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

据国际足联秘书长杰罗姆·瓦尔克说,贝老爷子的1950年版门票将在苏黎世的一家博物馆展出,展览定于2015年开放。他还说:“这版球票很稀有,我们希望博物馆能够珍藏。”
“温家宝总理强调指出,中国有效应对了全球金融危机的严重影响,经济保持稳定快速增长。因此中国成为全球第二大经济体,在五年内GDP几乎翻番。”Luis Schmidt Montes, Chilean ambassador

伊纳里图表示:“我差点忘记感谢所有参与拍摄的美国印第安人了,没有他们,这部电影不可能拍摄出来。我能够和这些人一起活着拍完这部电影,心中的惊喜和骄傲难以用语言表达。”
Next year, the mayor’s affordable housing plan, which calls for building or preserving 200,000 units of affordable housing over the next decade, will begin to take shape. It hinges on a policy that requires developers to build affordable housing in exchange for being allowed to construct taller and denser buildings in neighborhoods rezoned by the city. Developers and housing advocates alike are waiting to see what it will look like once the administration adds muscle and flesh to the bones of the proposal.
今年中国内地共有54所高校进入亚洲大学排行榜前300名。
经济学家原本还预计,今年1至10月份全国固定资产投资(不含农户)增长速度会与1至9月份的增长速度8.2%持平。
The bulk of the risk in this move comes with the possibility that both Ibaka and Turner are free agents this summer, but the disappointment that might result from losing one or both would pale in comparison of a postseason flameout in May.
这是两部后自语核(post-mumblecore)喜剧,讲述自我认知及其边界的故事。布西内斯克的影片是完美的怪人三角,三条边分别是盖·皮尔斯(Guy Pearce)、寇碧·史莫德斯(Cobie Smulders)和凯文·科利根(Kevin Corrigan),以德克萨斯州奥斯汀怪人们轻松胡混的伪装出现。皮文的影片探索精神病以及日间电视节目的的黑暗疆域。由于克里斯汀·韦格(Kristen Wiig)的精彩演出(她饰演一个名叫爱丽丝·克里格的彩票得主),《欢迎来到我的世界》成了关于美国梦想者的精彩肖像,既令人不安,也鼓舞人心。

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


政策红利有望逐渐释放 中国创新发展迎来机遇期


References

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2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


《被撕破的芭蕾舞鞋和突变的生活》(Torn Ballet Shoes, and a Life Upended)
紧缩政策促使一些企业寻求其他融资方案,比如债券或在全国中小企业股份转让系统上市。
莱昂纳多凭借他在《荒野猎人》中的演出斩获最佳男演员奖项,打败了埃迪·雷德梅尼等劲敌。埃迪凭借在《丹麦女孩》中的演出获得金球奖提名。坊间盛传小李子有望在今年夺得他人生中第一座奥斯卡奖杯。
intelligence
They expect the heat to get much worse over coming decades, but already it is killing forests around the world, driving plants and animals to extinction, melting land ice and causing the seas to rise at an accelerating pace.
James Kynge
至于英国,官方虚构数据同样盛行。英国国家统计局(Office For National Statistics)周二公布,以由来已久的零售价格指数(RPI)衡量,去年12月英国通胀率上升至4.1%。该数字纯属胡扯,英国国家统计局对此心知肚明。该机构告诉人们RPI“没有达到规定标准”,不能作为合格的通胀指标,但自2012年以来该机构一直拒绝采取措施来改善该指标并使之贴近3%的整体通胀率。
准时完成你的工作。即使还有额外的任务,也要如此。
4、《美国队长3:内战》
4. The 2012 Ig Nobel Neuroscience Prize

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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选择出国继续学习的学生比例也出现小幅下降,由去年的4.8%下降至3.4%。
Here are some of the trends that emerge from this year’s BrandZ rankings:
发型。略长的卷发——蛤?你不是自来卷哦?小可怜,那你只好每晚带着卷发夹入睡了。
D'ALOISIO HAS BEEN quoted opining that 'time is the new currency.' It's the driving notion behind Summly. It's also a strangely wise observation from a 17-year-old. At that age, many of us had more time on our hands than we knew how to fill without plummeting into severe boredom. It's easy to forget-conversing over lunch in a London caf钼 or strolling through the Tate Modern-that D'Aloisio was born in 1995 and has not yet graduated from high school. Or that he still lives in his childhood bedroom, in a cozy upper-middle-class home. As I chat with his parents, he excuses himself to work on his computer. Slouching down the hall in his stocking feet, hems of his skinny jeans brushing the hallway carpet, it is the most kidlike you will ever see him.

Lawyers are inherently cautious but most have realised that technology is crucial to crunching through the vast amount of information they handle. Without it, certain document heavy processes, such as disclosure and compliance, would be nearly impossible.

  • Only the first three authors are listed, followed by "et al."
  • 未来总人口将突破2000万 广州跻身全球超级城市
  • 压业主价抬成交价 广州黑中介违规手段多


而其他的队伍还有在尝试赢球的。小牛队,在3-13的战绩面前,骄傲地说他们不会垫底。但是,明年被认为是近年来最好的NBA选秀,有Markelle Fultz, Jayson Tatum, Lonzo Ball, Josh Jackson, Harry Gile, OG Anumoby, Ivan Rabb……等等优质球员。
上周,希拉里的竞选团队负责人约翰·波德斯塔表示,希拉里很可能会挑选一名女性作为她的副总统获选人。很快有人猜测,为了吸引女性选民,她的竞选伙伴很可能是马萨诸塞州参议员伊莉莎白·华伦。她是一名非常受女性欢迎的、激进的参选者。

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